How Antioxidants Support Male Fertility: Understanding the Research Behind Vitamen Boost

According to the World Health Organization, male factor infertility accounts for 50% of all infertility cases ^[6]. This is often due to impaired sperm parameters, including motility, morphology, and sperm count ^[7]. Oxidative stress, a condition caused by an excess of reactive oxygen species (ROS), has been identified as a key contributor to sperm dysfunction. Vitamen Boost provides a blend of antioxidant nutrients aimed at reducing this damage and supporting sperm health.

How Oxidative Stress Affects Male Fertility

Sperm cells are particularly vulnerable to oxidative damage due to their high polyunsaturated fat content and limited cytoplasmic antioxidant defences. Elevated ROS can lead to:

• DNA fragmentation
• Lipid peroxidation of the sperm membrane
• Reduced motility and viability
• Abnormal morphology

Key Antioxidants Supporting Sperm Parameters

Several nutrients have been studied for their ability to counteract oxidative stress and improve sperm function:

• Vitamin E (Tocopherol): A potent antioxidant that helps stabilise cell membranes and protect sperm from oxidative and heavy metal-induced damage ^[1][2][3].
• Vitamin C: Regenerates oxidised vitamin E and protects sperm DNA from damage.
• L-carnitine: Transports long-chain fatty acids into mitochondria, enhancing sperm energy metabolism and motility ^[4][5].
• L-arginine: A semi-essential amino acid shown to support sperm count and motility through nitric oxide-mediated vasodilation and improved blood flow.
• Coenzyme Q10: Supports mitochondrial energy production and has been linked to improved sperm motility and morphology.
• Vitamin B12: Involved in DNA synthesis and associated with improved sperm concentration and motility.

Evidence from Systematic Reviews

A systematic review of antioxidant types and doses concluded that supplementation improved key sperm parameters—including count, motility, morphology—as well as fertilisation and live birth rates in assisted reproduction settings ^[1].

Another meta-analysis of randomised clinical trials found that antioxidant intake led to statistically significant improvements in sperm motility and concentration ^[5].

References

1. Majzoub A., Agarwal A. (2018). Systematic review of antioxidant types and doses in male infertility. Arab. J. Urol., 16:113–124. doi:10.1016/j.aju.2017.11.013.
2. Rao M., Sharma P.S. (2001). Protective effect of vitamin E against mercuric chloride reproductive toxicity in male mice. Reprod. Toxicol., 15:705–712.
3. Giahi L. et al. (2016). Nutritional modifications in male infertility: A systematic review. Nutrit. Rev., 74:118–130.
4. Salas-Huetos A. et al. (2019). Diet and sperm quality: Nutrients, foods and dietary patterns. Reprod. Biol., 19:219–224.
5. Salas-Huetos A. et al. (2018). Nutrients and supplements on sperm quality: Meta-analysis of RCTs. Adv. Nutr., 9:833–848.
6. World Health Organization. (2018). Infertility Fact Sheet. WHO
7. Patel AS et al. (2017). Prediction of male infertility by WHO semen criteria. Arab J. Urol., 16:96–102.