Why Does Inflammation Affect Fertility and What Can You Do About It?
How chronic inflammation quietly affects fertility, and what to do about it.
Article
Posted on
PCOS is now PMOS. Here is what the new name means for your hormones, fertility and wellbeing.

If you have lived with PCOS, the news that the condition has a new name may feel both surprising and long overdue. After more than a decade of global consultation, PCOS is now officially known as PMOS, a change designed to better reflect what is really happening inside the body.
This is more than a rebrand. It is a recognition that millions of women have been navigating a misunderstood condition under a label that never told the full story.
The international community of researchers, clinicians and patient advocates announced the name change in 2026, following a process that spanned 14 years, gathered more than 22,000 survey responses and involved over 56 organisations worldwide.
The original name, Polycystic Ovary Syndrome, was considered misleading because the spots seen on ultrasound were never actually cysts, and because the condition affects far more than the ovaries.
The new name, PMOS, stands for Polyendocrine Metabolic Ovarian Syndrome. The word metabolic reflects what researchers and clinicians have long understood, that this is a whole body hormonal and metabolic condition, not simply an ovarian one.
PMOS is a complex hormonal and metabolic condition that influences how the body produces and responds to hormones, how it processes insulin and how it regulates energy, mood, skin and fertility.
It can present very differently from one woman to another, and even within the same woman across different life stages, from adolescence through to perimenopause.
PMOS affects around 1 in 8 women, with more than 170 million women living with the condition worldwide, making it one of the most common hormonal conditions in the world.1
Breaking down the new name
Despite the original name, the small spots seen on an ovarian ultrasound were never true cysts. They are immature egg follicles that have not progressed through ovulation as expected.
Recent research confirms that women with PMOS do not have an increased number of abnormal ovarian cysts, which is part of the reason clinicians felt the old name no longer reflected the science.
This shift in language matters, because the word cyst has caused unnecessary worry for many women over the years.
The diagnostic criteria have not changed. A diagnosis is still made when a woman meets two out of three of the following:
If you have already been diagnosed with PCOS, your diagnosis still stands. Nothing about your medical history needs to be revisited because of the name change.

Research suggests that up to 70 percent of women with PMOS remain undiagnosed, and those who are diagnosed often wait more than three years to receive answers.1
The old name contributed to this delay. Women without visible ovarian findings often felt dismissed, and the focus on cysts overshadowed the metabolic and hormonal signs that are central to the condition.
The hope is that the new name will open up clearer conversations with healthcare providers and help more women feel seen and heard sooner.
PMOS is associated with insulin resistance, which plays a role in many of the symptoms women experience, from energy dips to changes in skin and weight.
Over time, this can be linked with a higher risk of type 2 diabetes and may influence cardiovascular health, which is why a whole body approach is so important.
Mental health is also part of the picture. Research suggests that women with PMOS experience higher rates of depression and anxiety, and the condition can shift again during perimenopause, when hormonal changes bring a new layer of complexity.2
PMOS can disrupt ovulation, which is often the main reason women with the condition find conception more challenging.
The reassuring news is that PMOS tends to respond well to the right support. With the right nutritional, lifestyle and clinical guidance, many women go on to conceive, sometimes with medical help and sometimes naturally.
The aim is not to fight your body but to support it, gently and consistently, so that ovulation and hormonal balance have the best chance to settle.

Both names, PCOS and PMOS, will be used until 2028 while healthcare systems, research bodies and patient resources catch up.
In the meantime, you may see either name in clinics, on test results or in articles. If you prefer to use the new name in conversations with your GP or specialist, it can be a helpful way to open up a wider discussion about your metabolic and hormonal health.
Nutrition is one of the most powerful tools available for women with PMOS, because it works gently with the body's hormonal and metabolic systems. The following nutrients may support hormonal balance, ovulation and overall wellbeing.
Myo-inositol plays a role in how the body responds to insulin and supports healthy ovarian function. Research suggests it may support more regular ovulation in women with PMOS, and pairing it with methylfolate adds preconception support.3
Many women with PMOS are low in vitamin D, which is associated with hormonal balance, immune health and mood. Adequate levels may support healthy menstrual cycles and overall wellbeing.4
Omega 3s play a role in reducing inflammation and supporting cardiovascular and mental health, both of which are relevant for women with PMOS.
Zinc supports hormonal balance, skin health and reproductive function. It may be particularly helpful for women experiencing androgen related symptoms such as acne or excess hair growth.
N-Acetylcysteine (NAC), a dietary supplement known for its antioxidant properties, is emerging as a potential aid for women dealing with PMOS. Learn more here.
CoQ10 is involved in cellular energy production and is associated with egg quality. It may support women with PMOS who are trying to conceive, particularly from their mid thirties onwards.5
For those looking to support their PMOS journey, our support pack contains all of the supplements we recommend for this journey.
They are the same condition. PMOS is the new name, chosen to better reflect that this is a whole body hormonal and metabolic condition rather than simply an ovarian one.
No. The diagnostic criteria remain the same, based on meeting two out of three of irregular ovulation, elevated androgens and ovarian ultrasound findings.
Yes. Ovarian findings are only one of the three diagnostic criteria, and many women are diagnosed without them.
Not always. Some women conceive easily, while others need more support. PMOS tends to respond well to nutritional, lifestyle and clinical care.
Nutrients such as myo-inositol with methylfolate, vitamin D, omega 3s, zinc and CoQ10 may support hormonal and metabolic health, alongside a balanced diet.
Yes, if it feels useful. Using the new name can help open a wider conversation about your metabolic and hormonal health, not just your ovaries.
Start with your GP, who can arrange initial investigations. You can also seek guidance from fertility and hormonal health specialists, and from trusted nutritional experts.
How chronic inflammation quietly affects fertility, and what to do about it.
What sperm DNA fragmentation means and how to support healthy sperm before conception.
Why choline matters for fertility, egg quality and early pregnancy.